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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HCK
All Species:
7.27
Human Site:
S68
Identified Species:
16
UniProt:
P08631
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P08631
NP_002101.2
526
59600
S68
P
G
P
N
S
H
N
S
N
T
P
G
I
R
E
Chimpanzee
Pan troglodytes
XP_514571
635
71442
S181
P
G
P
N
S
N
N
S
N
T
P
G
I
R
E
Rhesus Macaque
Macaca mulatta
XP_001087049
602
68092
G143
P
E
S
Q
L
L
P
G
Q
R
F
Q
A
K
D
Dog
Lupus familis
XP_542952
627
70167
N169
K
R
R
P
D
H
S
N
D
N
L
P
G
S
K
Cat
Felis silvestris
Mouse
Mus musculus
P08103
524
59111
N66
K
L
G
P
N
N
S
N
S
M
P
P
G
F
V
Rat
Rattus norvegicus
P50545
524
59135
N66
K
L
G
P
N
S
I
N
S
L
P
P
G
V
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514812
514
58948
D62
G
Q
R
F
Q
S
K
D
P
E
E
Q
G
V
I
Chicken
Gallus gallus
P42683
508
58121
D62
P
P
C
S
P
L
Q
D
K
L
V
V
A
L
Y
Frog
Xenopus laevis
P13406
537
60828
T73
G
V
N
S
S
S
H
T
G
T
L
R
T
R
G
Zebra Danio
Brachydanio rerio
XP_698462
1009
113199
T553
G
A
K
A
N
R
T
T
S
N
A
Q
T
P
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V9J3
517
59051
N64
E
S
E
T
A
G
A
N
A
K
I
F
V
A
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
80.3
61.1
76.7
N.A.
89.7
89.5
N.A.
68.8
64
56.6
42
N.A.
52.2
N.A.
N.A.
N.A.
Protein Similarity:
100
81
72.9
79.9
N.A.
94.8
94.4
N.A.
82.3
78.3
72.4
47.2
N.A.
67.1
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
6.6
6.6
N.A.
6.6
6.6
N.A.
0
6.6
20
0
N.A.
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
20
33.3
N.A.
40
26.6
N.A.
0
13.3
40
20
N.A.
20
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
10
10
0
10
0
10
0
10
0
19
10
0
% A
% Cys:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
10
0
0
19
10
0
0
0
0
0
10
% D
% Glu:
10
10
10
0
0
0
0
0
0
10
10
0
0
0
19
% E
% Phe:
0
0
0
10
0
0
0
0
0
0
10
10
0
10
0
% F
% Gly:
28
19
19
0
0
10
0
10
10
0
0
19
37
0
19
% G
% His:
0
0
0
0
0
19
10
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
10
0
0
0
10
0
19
0
10
% I
% Lys:
28
0
10
0
0
0
10
0
10
10
0
0
0
10
10
% K
% Leu:
0
19
0
0
10
19
0
0
0
19
19
0
0
10
10
% L
% Met:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% M
% Asn:
0
0
10
19
28
19
19
37
19
19
0
0
0
0
0
% N
% Pro:
37
10
19
28
10
0
10
0
10
0
37
28
0
10
0
% P
% Gln:
0
10
0
10
10
0
10
0
10
0
0
28
0
0
0
% Q
% Arg:
0
10
19
0
0
10
0
0
0
10
0
10
0
28
0
% R
% Ser:
0
10
10
19
28
28
19
19
28
0
0
0
0
10
0
% S
% Thr:
0
0
0
10
0
0
10
19
0
28
0
0
19
0
0
% T
% Val:
0
10
0
0
0
0
0
0
0
0
10
10
10
19
19
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _